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Mechanistically, VB directly binds and downregulates CCN1, an oncogenic factor highly expressed in OC, inhibiting the AKT/NF-B pathway, which plays a central role in regulating tumor progression and macrophage polarization

Despite a recent global decrease in malaria incidence, this progress is reaching a plateau, with 229 million malaria cases in 2019 ( Plasmodium spp

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Investigation of the role of mitochondrial DNA in multiple sclerosis susceptibility

The growing consensus that many phylogenetically distinct intracellular pathogens rely on eukaryotic GSH for intracellular growth and survival may suggest that the reducing cytosol is a host-associated molecular pattern (HAMP)

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS